Platinum Concentration and Pathologic Response to Cisplatin-Based Neoadjuvant Chemotherapy in Muscle-Invasive Bladder Cancer

BACKGROUND: Platinum (Pt)-based chemotherapy is the standard of care for muscle-invasive bladder cancer (MIBC). However, resistance is a major limitation. Reduced intratumoral drug accumulation is an important mechanism of platinum resistance. Our group previously demonstrated a significant correlat...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Guancial, Elizabeth A., Kilari, Deepak, Xiao, Guang-Qian, Abu-Farsakh, Sohaib H., Baran, Andrea, Messing, Edward M., Kim, Eric S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871463/
https://ncbi.nlm.nih.gov/pubmed/27187160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155503
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