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Role of copper transporters in platinum resistance

Platinum (Pt)-based antitumor agents are effective in the treatment of many solid malignancies. However, their efficacy is limited by toxicity and drug resistance. Reduced intracellular Pt accumulation has been consistently shown to correlate with resistance in tumors. Proteins involved in copper ho...

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Detalhes bibliográficos
Publicado no:World J Clin Oncol
Main Authors: Kilari, Deepak, Guancial, Elizabeth, Kim, Eric S
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734932/
https://ncbi.nlm.nih.gov/pubmed/26862494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v7.i1.106
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