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Cystic fibrosis transmembrane conductance regulator activation by the solvent ethanol: implications for topical drug delivery
BACKGROUND: Decreased CFTR-mediated chloride (Cl) secretion across mucosal surfaces contributes to the development of airway disease by depleting airway surface liquid, increasing mucus viscosity and adhesion, and consequently hindering mucociliary clearance. We serendipitously discovered during tes...
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| Pubblicato in: | Int Forum Allergy Rhinol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4871113/ https://ncbi.nlm.nih.gov/pubmed/26869199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.21638 |
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