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Resveratrol enhances airway surface liquid depth in sinonasal epithelium by increasing cystic fibrosis transmembrane conductance regulator open probability.

Chronic rhinosinusitis engenders enormous morbidity in the general population, and is often refractory to medical intervention. Compounds that augment mucociliary clearance in airway epithelia represent a novel treatment strategy for diseases of mucus stasis. A dominant fluid and electrolyte secreto...

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Detalhes bibliográficos
Main Authors: Shaoyan Zhang, Angela C Blount, Carmel M McNicholas, Daniel F Skinner, Michael Chestnut, John C Kappes, Eric J Sorscher, Bradford A Woodworth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3839872?pdf=render
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