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Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes

In this work we demonstrate a label-free optical imaging technique to assess metabolic status and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes by two-photon fluorescence lifetime imaging of endogenous fluorophores. Our results show the sensitivity of this method to...

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Bibliografiske detaljer
Udgivet i:Biomed Opt Express
Main Authors: Datta, Rupsa, Heylman, Christopher, George, Steven C., Gratton, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: Optical Society of America 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871074/
https://ncbi.nlm.nih.gov/pubmed/27231614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.7.001690
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