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Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes

In this work we demonstrate a label-free optical imaging technique to assess metabolic status and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes by two-photon fluorescence lifetime imaging of endogenous fluorophores. Our results show the sensitivity of this method to...

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Publicat a:Biomed Opt Express
Autors principals: Datta, Rupsa, Heylman, Christopher, George, Steven C., Gratton, Enrico
Format: Artigo
Idioma:Inglês
Publicat: Optical Society of America 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871074/
https://ncbi.nlm.nih.gov/pubmed/27231614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.7.001690
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