Centrally Synthesized Estradiol Is a Potent Anti-Inflammatory in the Injured Zebra Finch Brain

In homeotherms, injury to the brain, such as a penetrating wound, increases microglial cytokine expression and astroglial aromatase (estrogen synthase). In songbirds, injury-induced synthesis of estrogens is neuroprotective as aromatase inhibition and replacement with estradiol (E(2)) exacerbates an...

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Detaylı Bibliyografya
Yayımlandı:Endocrinology
Asıl Yazarlar: Pedersen, Alyssa L., Nelson, Lars H., Saldanha, Colin J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2016
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870876/
https://ncbi.nlm.nih.gov/pubmed/26963472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1991
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