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Centrally Synthesized Estradiol Is a Potent Anti-Inflammatory in the Injured Zebra Finch Brain
In homeotherms, injury to the brain, such as a penetrating wound, increases microglial cytokine expression and astroglial aromatase (estrogen synthase). In songbirds, injury-induced synthesis of estrogens is neuroprotective as aromatase inhibition and replacement with estradiol (E(2)) exacerbates an...
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| Publié dans: | Endocrinology |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Endocrine Society
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870876/ https://ncbi.nlm.nih.gov/pubmed/26963472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1991 |
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