Islet Hypersensitivity to Glucose Is Associated With Disrupted Oscillations and Increased Impact of Proinflammatory Cytokines in Islets From Diabetes-Prone Male Mice

Pulsatile insulin release is the primary means of blood glucose regulation. The loss of pulsatility is thought to be an early marker and possible factor in developing type 2 diabetes. Another early adaptation in islet function to compensate for obesity is increased glucose sensitivity (left shift) a...

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Detaylı Bibliyografya
Yayımlandı:Endocrinology
Asıl Yazarlar: Corbin, Kathryn L., Waters, Christopher D., Shaffer, Brett K., Verrilli, Gretchen M., Nunemaker, Craig S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2016
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870867/
https://ncbi.nlm.nih.gov/pubmed/26943366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1879
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