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Chronic stimulation induces adaptive potassium channel activity that restores calcium oscillations in pancreatic islets in vitro
Insulin pulsatility is important to hepatic response in regulating blood glucose. Growing evidence suggests that insulin-secreting pancreatic β-cells can adapt to chronic disruptions of pulsatility to rescue this physiologically important behavior. We determined the time scale for adaptation and exa...
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| 出版年: | Am J Physiol Endocrinol Metab |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7191410/ https://ncbi.nlm.nih.gov/pubmed/32069073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00482.2019 |
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