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Ablation of KNDy Neurons Results in Hypogonadotropic Hypogonadism and Amplifies the Steroid-Induced LH Surge in Female Rats

In the human infundibular (arcuate) nucleus, a subpopulation of neurons coexpress kisspeptin and neurokinin B (NKB), 2 peptides required for normal reproductive function. A homologous group of neurons exists in the arcuate nucleus of rodents, termed KNDy neurons based on the coexpression of kisspept...

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Publicat a:Endocrinology
Autors principals: Mittelman-Smith, Melinda A., Krajewski-Hall, Sally J., McMullen, Nathaniel T., Rance, Naomi E.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870865/
https://ncbi.nlm.nih.gov/pubmed/26937713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1740
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