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Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: A novel hypothesis on the mechanism of hot flushes

Despite affecting millions of individuals, the etiology of hot flushes remains unknown. Here we review the physiology of hot flushes, CNS pathways regulating heat-dissipation effectors, and effects of estrogen on thermoregulation in animal models. Based on the marked changes in hypothalamic kisspept...

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Библиографические подробности
Главные авторы: Rance, Naomi E., Dacks, Penny A., Mittelman-Smith, Melinda A., Romanovsky, Andrej A., Krajewski-Hall, Sally J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833827/
https://ncbi.nlm.nih.gov/pubmed/23872331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yfrne.2013.07.003
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