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Long-term expression of miRNA for RNA interference using a novel vector system based on a negative-strand RNA virus
RNA interference (RNAi) has emerged as a promising technique for gene therapy. However, the safe and long-term expression of small RNA molecules is a major concern for the application of RNAi therapies in vivo. Borna disease virus (BDV), a non-segmented, negative-strand RNA virus, establishes a pers...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870639/ https://ncbi.nlm.nih.gov/pubmed/27189575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26154 |
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