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Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis

Pancreatic tumors exhibit enhanced autophagy as compared to any other cancer, making it resistant to chemotherapy. We evaluated the effect of penfluridol against pancreatic cancer. Penfluridol treatment induced apoptosis and inhibited the growth of Panc-1, BxPC-3 and AsPC-1, pancreatic cancer cells...

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書目詳細資料
發表在:Sci Rep
Main Authors: Ranjan, Alok, Srivastava, Sanjay K.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870635/
https://ncbi.nlm.nih.gov/pubmed/27189859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26165
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