Assessing mutant p53 in primary high-grade serous ovarian cancer using immunohistochemistry and massively parallel sequencing

The tumour suppressor p53 is mutated in cancer, including over 96% of high-grade serous ovarian cancer (HGSOC). Mutations cause loss of wild-type p53 function due to either gain of abnormal function of mutant p53 (mutp53), or absent to low mutp53. Massively parallel sequencing (MPS) enables increase...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cole, Alexander J., Dwight, Trisha, Gill, Anthony J., Dickson, Kristie-Ann, Zhu, Ying, Clarkson, Adele, Gard, Gregory B., Maidens, Jayne, Valmadre, Susan, Clifton-Bligh, Roderick, Marsh, Deborah J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870633/
https://ncbi.nlm.nih.gov/pubmed/27189670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26191
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados