Sirt6 cooperates with Blimp1 to positively regulate osteoclast differentiation

Global deletion of the gene encoding a nuclear histone deacetylase sirtuin 6 (Sirt6) in mice leads to osteopenia with a low bone turnover due to impaired bone formation. But whether Sirt6 regulates osteoclast differentiation is less clear. Here we show that Sirt6 functions as a transcriptional regul...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Park, So Jeong, Huh, Jeong-Eun, Shin, Jihye, Park, Doo Ri, Ko, Ryeojin, Jin, Gyu-Rin, Seo, Dong-Hyun, Kim, Han-Sung, Shin, Hong-In, Oh, Goo Taeg, Kim, Hyun Seok, Lee, Soo Young
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870620/
https://ncbi.nlm.nih.gov/pubmed/27189179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26186
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items