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Construction of AAV-rat-IL4 and Evaluation of its Modulating Effect on Aβ (1-42)-Induced Proinflammatory Cytokines in Primary Microglia and the B92 Cell Line by Quantitative PCR Assay

BACKGROUND: Interleukin-4 (IL-4), as the most prominent anti-inflammatory cytokine, plays an important role in modulating microglial activation and inflammatory responses in Alzheimer’s disease (AD), a chronic inflammatory disorder. OBJECTIVES: The current study aimed to develop a new recombinant Ad...

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Detalhes bibliográficos
Publicado no:Jundishapur J Microbiol
Main Authors: Jamalidoust, Marzieh, Ravanshad, Mehrdad, Namayandeh, Mandana, Zare, Maryam, Asaei, Sadaf, Ziyaeyan, Mazyar
Formato: Artigo
Idioma:Inglês
Publicado em: Kowsar 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870549/
https://ncbi.nlm.nih.gov/pubmed/27217922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/jjm.30444
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