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Construction of AAV-rat-IL4 and Evaluation of its Modulating Effect on Aβ (1-42)-Induced Proinflammatory Cytokines in Primary Microglia and the B92 Cell Line by Quantitative PCR Assay
BACKGROUND: Interleukin-4 (IL-4), as the most prominent anti-inflammatory cytokine, plays an important role in modulating microglial activation and inflammatory responses in Alzheimer’s disease (AD), a chronic inflammatory disorder. OBJECTIVES: The current study aimed to develop a new recombinant Ad...
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| Udgivet i: | Jundishapur J Microbiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Kowsar
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870549/ https://ncbi.nlm.nih.gov/pubmed/27217922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/jjm.30444 |
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