Augmentation of Recipient Adaptive Alloimmunity by Donor Passenger Lymphocytes within the Transplant

Chronic rejection of solid organ allografts remains the major cause of transplant failure. Donor-derived tissue-resident lymphocytes are transferred to the recipient during transplantation, but their impact on alloimmunity is unknown. Using mouse cardiac transplant models, we show that graft-versus-...

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Publicat a:Cell Rep
Autors principals: Harper, Ines G., Ali, Jason M., Harper, Simon J.F., Wlodek, Elizabeth, Alsughayyir, Jawaher, Negus, Margaret C., Qureshi, M. Saeed, Motalleb-Zadeh, Reza, Saeb-Parsy, Kourosh, Bolton, Eleanor M., Bradley, J. Andrew, Clatworthy, Menna R., Conlon, Thomas M., Pettigrew, Gavin J.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870521/
https://ncbi.nlm.nih.gov/pubmed/27134179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.009
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