Isolation and Molecular Profiling of Primary Mouse Retinal Ganglion Cells: Comparison of Phenotypes from Healthy and Glaucomatous Retinas

Loss of functional retinal ganglion cells (RGC) is an element of retinal degeneration that is poorly understood. This is in part due to the lack of a reliable and validated protocol for the isolation of primary RGCs. Here we optimize a feasible, reproducible, standardized flow cytometry-based protoc...

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Vydáno v:Front Aging Neurosci
Hlavní autoři: Chintalapudi, Sumana R., Djenderedjian, Levon, Stiemke, Andrew B., Steinle, Jena J., Jablonski, Monica M., Morales-Tirado, Vanessa M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870266/
https://ncbi.nlm.nih.gov/pubmed/27242509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00093
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