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The Alzheimer’s disease peptide Aβ promotes thrombin generation through activation of coagulation factor XII
BACKGROUND: Beta-amyloid (Aβ) is a key pathological element in Alzheimer’s disease (AD), but the mechanisms by which it disrupts neuronal function in vivo are not completely understood. AD is characterized by a prothrombotic state, which could contribute to neuronal dysfunction by affecting cerebral...
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| Pubblicato in: | J Thromb Haemost |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870142/ https://ncbi.nlm.nih.gov/pubmed/26613657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13209 |
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