Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

Dynamic cellular systems reprogram gene expression to ensure appropriate cellular fate responses to specific extracellular cues. Here we demonstrate that the dynamics of Nuclear Factor kappa B (NF-κB) signalling and the cell cycle are prioritised differently depending on the timing of an inflammator...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ankers, John M, Awais, Raheela, Jones, Nicholas A, Boyd, James, Ryan, Sheila, Adamson, Antony D, Harper, Claire V, Bridge, Lloyd, Spiller, David G, Jackson, Dean A, Paszek, Pawel, Sée, Violaine, White, Michael RH
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869934/
https://ncbi.nlm.nih.gov/pubmed/27185527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10473
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