The effect of dipyridamole on the pharmacokinetics of metformin: a randomized crossover study in healthy volunteers

PURPOSE: Concomitant treatment with the glucose-lowering drug metformin and the platelet aggregation inhibitor dipyridamole often occurs in patients with type 2 diabetes mellitus who have suffered a cerebrovascular event. The gastrointestinal uptake of metformin is mediated by the human equilibrativ...

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Vydáno v:Eur J Clin Pharmacol
Hlavní autoři: El Messaoudi, S., Russel, F. G., Colbers, A., Bandell, C. C. J. G., van den Broek, P. H. H., Burger, D. M., Rongen, G. A., Riksen, N. P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2016
Témata:
Pharmacokinetics and Disposition
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869751/
https://ncbi.nlm.nih.gov/pubmed/26979520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-016-2039-8
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