Cavitation as a Mechanism of Substrate Discrimination by Adenylosuccinate Synthetases()

Adenylosuccinate synthetase catalyzes the first committed step in the de novo biosynthesis of AMP, coupling L-aspartate and IMP to form adenylosuccinate. K(m) values of IMP and 2′-deoxy-IMP are nearly identical with each substrate supporting comparable maximal velocities. Nonetheless, the K(m) value...

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Bibliografiska uppgifter
I publikationen:Biochemistry
Huvudupphovsmän: Iancu, Cristina V., Zhou, Yang, Borza, Tudor, Fromm, Herbert J., Honzatko, Richard B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869520/
https://ncbi.nlm.nih.gov/pubmed/16981730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0607498
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