High frequency of single-base transitions and extreme frequency of precise multiple-base reversion mutations in poliovirus.
We employed independent clones of a temperature-sensitive mutant of type 1 poliovirus, 3AB-310/4, to quantitate the frequency of specific U----C transitions at nucleotide 5310, within the genomic region encoding polypeptide 3AB, which is involved in the initiation of RNA replication. Only this U----...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1992
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2531 |
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