High frequency of single-base transitions and extreme frequency of precise multiple-base reversion mutations in poliovirus.

We employed independent clones of a temperature-sensitive mutant of type 1 poliovirus, 3AB-310/4, to quantitate the frequency of specific U----C transitions at nucleotide 5310, within the genomic region encoding polypeptide 3AB, which is involved in the initiation of RNA replication. Only this U----...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	de la Torre, J C, Giachetti, C, Semler, B L, Holland, J J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2531
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