Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation

BACKGROUND: Breast cancer risk increases drastically in individuals carrying a germline BRCA1 mutation. The exposure to ionizing radiation for diagnostic or therapeutic purposes of BRCA1 mutation carriers is counterintuitive, since BRCA1 is active in the DNA damage response pathway. The aim of this...

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書目詳細資料
發表在:Breast Cancer Res
Main Authors: Baert, Annelot, Depuydt, Julie, Van Maerken, Tom, Poppe, Bruce, Malfait, Fransiska, Storm, Katrien, van den Ende, Jenneke, Van Damme, Tim, De Nobele, Sylvia, Perletti, Gianpaolo, De Leeneer, Kim, Claes, Kathleen B. M., Vral, Anne
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869288/
https://ncbi.nlm.nih.gov/pubmed/27184744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0709-1
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