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Mediator subunit Med12 contributes to the maintenance of neural stem cell identity

BACKGROUND: The RNA polymerase II transcriptional Mediator subunit Med12 is broadly implicated in vertebrate brain development, and genetic variation in human MED12 is associated with X-linked intellectual disability and neuropsychiatric disorders. Although prior studies have begun to elaborate the...

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Udgivet i:BMC Dev Biol
Main Authors: Kim, Nam Hee, Livi, Carolina B., Yew, P. Renee, Boyer, Thomas G.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869265/
https://ncbi.nlm.nih.gov/pubmed/27188461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-016-0114-0
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