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Brain Tumor Genetic Modification Yields Increased Resistance to Paclitaxel in Physical Confinement

Brain tumor cells remain highly resistant to radiation and chemotherapy, particularly malignant and secondary cancers. In this study, we utilized microchannel devices to examine the effect of a confined environment on the viability and drug resistance of the following brain cancer cell lines: primar...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bui, Loan, Hendricks, Alissa, Wright, Jamie, Chuong, Cheng-Jen, Davé, Digant, Bachoo, Robert, Kim, Young-tae
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869028/
https://ncbi.nlm.nih.gov/pubmed/27184621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26134
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