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Molecular determinants of plaque size as an indicator of dengue virus attenuation
The development of live viral vaccines relies on empirically derived phenotypic criteria, especially small plaque sizes, to indicate attenuation. However, while some candidate vaccines successfully translated into licensed applications, others have failed safety trials, placing vaccine development o...
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| Published in: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868997/ https://ncbi.nlm.nih.gov/pubmed/27185466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26100 |
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