Molecular determinants of plaque size as an indicator of dengue virus attenuation

The development of live viral vaccines relies on empirically derived phenotypic criteria, especially small plaque sizes, to indicate attenuation. However, while some candidate vaccines successfully translated into licensed applications, others have failed safety trials, placing vaccine development o...

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Publicat a:Sci Rep
Autors principals: Goh, Kenneth Choon Meng, Tang, Choon Kit, Norton, Diana Catherine, Gan, Esther Shuyi, Tan, Hwee Cheng, Sun, Bo, Syenina, Ayesa, Yousuf, Amjad, Ong, Xin Mei, Kamaraj, Uma Sangumathi, Cheung, Yin Bun, Gubler, Duane J, Davidson, Andrew, St John, Ashley Lauren, Sessions, October Michael, Ooi, Eng Eong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868997/
https://ncbi.nlm.nih.gov/pubmed/27185466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26100
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