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Vitamin-D receptor agonist calcitriol reduces calcification in vitro through selective upregulation of SLC20A2 but not SLC20A1 or XPR1

Vitamin D deficiency (hypovitaminosis D) causes osteomalacia and poor long bone mineralization. In apparent contrast, hypovitaminosis D has been reported in patients with primary brain calcifications (“Fahr’s disease”). We evaluated the expression of two phosphate transporters which we have found to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Keasey, M. P., Lemos, R. R., Hagg, T., Oliveira, J. R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868979/
https://ncbi.nlm.nih.gov/pubmed/27184385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25802
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