Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis

Solute carrier family 20 member 2 (SLC20A2) and xenotropic and polytropic retrovirus receptor 1 (XPR1) are transporters with phosphate uptake and efflux functions, respectively. Both are associated with primary familial brain calcification (PFBC), a genetic disease characterized by cerebral calcium-...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: López-Sánchez, Uriel, Tury, Sandrine, Nicolas, Gaël, Wilson, Miranda S., Jurici, Snejana, Ayrignac, Xavier, Courgnaud, Valérie, Saiardi, Adolfo, Sitbon, Marc, Battini, Jean-Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363132/
https://ncbi.nlm.nih.gov/pubmed/32393577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011376
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