TGF-β-induced regulatory T cells directly suppress B cell responses through a non-cytotoxic mechanism

Foxp3(+) regulatory T cells (Treg) playing a crucial role in the maintenance of immune tolerance and prevention of autoimmune diseases consist of thymus-derived naturally-occurring CD4(+)Foxp3(+) Treg cells (nTreg) and those that can be induced ex vivo with TGF-β (iTreg). Although both Treg subsets...

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Pubblicato in:J Immunol
Autori principali: Xu, Anping, Liu, Ya, Chen, Weiqian, Wang, Julie, Xue, Youqiu, Huang, Feng, Rong, liming, Lin, Jin, Liu, Dahai, Yan, Mei, Li, Quan-Zhen, Li, Bin, Song, Jianxun, Olsen, Nancy, Zheng, Song Guo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868785/
https://ncbi.nlm.nih.gov/pubmed/27001954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501740
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