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Metabolic reprogramming of host cells by virulent Francisella tularensis for optimal replication and modulation of inflammation
A shift in macrophage metabolism from oxidative phosphorylation to aerobic glycolysis is a requirement for activation to effectively combat invading pathogens. Francisella tularensis is a facultative intracellular bacterium that causes an acute, fatal disease called tularemia. Its primary mechanism...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868765/ https://ncbi.nlm.nih.gov/pubmed/27029588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502456 |
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