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A novel role for plasmin mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis

Opsonization by antibodies represents a critical component of the host immune response against many pathogens. The mechanisms by which virulent microbes evade this protective response are not completely understood. In disease mediated by Francisella tularensis, antibody can effectively protect again...

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Main Authors: Crane, Deborah D., Warner, Shayna L., Bosio, Catharine M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748154/
https://ncbi.nlm.nih.gov/pubmed/19752236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901655
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