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MOV10 provides antiviral activity against RNA viruses by enhancing RIG-I-MAVS-independent IFN induction

MOV10 (Moloney leukemia virus 10, homolog) is an interferon-inducible RNA helicase, associated with small RNA-induced silencing. Here, we report that MOV10 exhibits antiviral activity, independent of its helicase function, against a number of positive and negative-strand RNA viruses by enhancing typ...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Cuevas, Rolando A., Ghosh, Arundhati, Wallerath, Christina, Hornung, Veit, Coyne, Carolyn B., Sarkar, Saumendra N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868630/
https://ncbi.nlm.nih.gov/pubmed/27016603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501359
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