Llwytho...

Programmable RNA-binding protein composed of repeats of a single modular unit

The ability to monitor and perturb RNAs in living cells would benefit greatly from a modular protein architecture that targets unmodified RNA sequences in a programmable way. We report that the RNA-binding protein PumHD (Pumilio homology domain), which has been widely used in native and modified for...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Adamala, Katarzyna P., Martin-Alarcon, Daniel A., Boyden, Edward S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868411/
https://ncbi.nlm.nih.gov/pubmed/27118836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519368113
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