Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response

The heat shock protein gp96 elicits specific T cell responses to its chaperoned peptides against cancer and infectious diseases in both rodent models and clinical trials. Although gp96-induced innate immunity, via a subset of Toll like receptors (TLRs), and adaptive immunity, through antigen present...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Weiwei, Chen, Mi, Li, Xinghui, Zhao, Bao, Hou, Junwei, Zheng, Huaguo, Qiu, Lipeng, Li, Zihai, Meng, Songdong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868323/
https://ncbi.nlm.nih.gov/pubmed/27183126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155202
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