Combinatory effect of BRCA1 and HERC2 expression on outcome in advanced non-small-cell lung cancer

BACKGROUND: BRCA1 is a main component of homologous recombination and induces resistance to platinum in preclinical models. It has been studied as a potential predictive marker in lung cancer. Several proteins modulate the function of BRCA1. The E3 ubiquitin ligase HERC2 facilitates the assembly of...

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發表在:BMC Cancer
Main Authors: Bonanno, Laura, Costa, Carlota, Majem, Margarita, Sanchez, Jose-Javier, Rodriguez, Ignacio, Gimenez-Capitan, Ana, Molina-Vila, Miquel Angel, Vergnenegre, Alain, Massuti, Bartomeu, Favaretto, Adolfo, Rugge, Massimo, Pallares, Cinta, Taron, Miquel, Rosell, Rafael
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868003/
https://ncbi.nlm.nih.gov/pubmed/27179511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2339-5
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