The Prognostic Value of BRCA1 mRNA Expression Levels Following Neoadjuvant Chemotherapy in Breast Cancer

BACKGROUND: A fraction of sporadic breast cancers has low BRCA1 expression. BRCA1 mutation carriers are more likely to achieve a pathological complete response with DNA-damage-based chemotherapy compared to non-mutation carriers. Furthermore, sporadic ovarian cancer patients with low levels of BRCA1...

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Autori principali: Margeli, Mireia, Cirauqui, Beatriz, Castella, Eva, Tapia, Gustavo, Costa, Carlota, Gimenez-Capitan, Ana, Barnadas, Agusti, Ronco, Maria Sanchez, Benlloch, Susana, Taron, Miquel, Rosell, Rafael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831058/
https://ncbi.nlm.nih.gov/pubmed/20209131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009499
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