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Tumor-associated fibroblasts promote the proliferation and decrease the doxorubicin sensitivity of liposarcoma cells

The reasons for the distinct chemoresistance of liposarcomas and their high risk of local recurrence still remain unclear. Depending on the histological subtype of liposarcoma, first-line therapy with the cytostatic agent, doxorubicin, only achieves response rates of approximately 36%. Approximatley...

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Bibliografske podrobnosti
izdano v:Int J Mol Med
Main Authors: HARATI, KAMRAN, DAIGELER, ADRIEN, HIRSCH, TOBIAS, JACOBSEN, FRANK, BEHR, BJÖRN, WALLNER, CHRISTOPH, LEHNHARDT, MARCUS, BECERIKLI, MUSTAFA
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867885/
https://ncbi.nlm.nih.gov/pubmed/27082154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2556
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