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Tumor-associated fibroblasts promote the proliferation and decrease the doxorubicin sensitivity of liposarcoma cells

The reasons for the distinct chemoresistance of liposarcomas and their high risk of local recurrence still remain unclear. Depending on the histological subtype of liposarcoma, first-line therapy with the cytostatic agent, doxorubicin, only achieves response rates of approximately 36%. Approximatley...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: HARATI, KAMRAN, DAIGELER, ADRIEN, HIRSCH, TOBIAS, JACOBSEN, FRANK, BEHR, BJÖRN, WALLNER, CHRISTOPH, LEHNHARDT, MARCUS, BECERIKLI, MUSTAFA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867885/
https://ncbi.nlm.nih.gov/pubmed/27082154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2556
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