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Distributing a metabolic pathway among a microbial consortium enhances production of natural products

Metabolic engineering of microorganisms such as Escherichia coli and Saccharomyces cerevisiae to produce high-value natural metabolites is often done through functional reconstitution of long metabolic pathways. Problems arise when parts of pathways require specialized environments or compartments f...

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Vydáno v:Nat Biotechnol
Hlavní autoři: Zhou, Kang, Qiao, Kangjian, Edgar, Steven, Stephanopoulos, Gregory
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867547/
https://ncbi.nlm.nih.gov/pubmed/25558867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3095
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