Intestinal-specific activatable Myb initiates colon tumorigenesis in mice

Transcription factor Myb is overexpressed in most colorectal cancers (CRC). Patients with CRC expressing the highest Myb are more likely to relapse. We previously showed that mono-allelic loss of Myb in an Adenomatous polyposis coli (APC)-driven CRC mouse model (Apc(Min/+)) significantly improves su...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Malaterre, J, Pereira, L, Putoczki, T, Millen, R, Paquet-Fifield, S, Germann, M, Liu, J, Cheasley, D, Sampurno, S, Stacker, S A, Achen, M G, Ward, R L, Waring, P, Mantamadiotis, T, Ernst, M, Ramsay, R G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867492/
https://ncbi.nlm.nih.gov/pubmed/26300002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.305
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