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Intestinal-specific activatable Myb initiates colon tumorigenesis in mice
Transcription factor Myb is overexpressed in most colorectal cancers (CRC). Patients with CRC expressing the highest Myb are more likely to relapse. We previously showed that mono-allelic loss of Myb in an Adenomatous polyposis coli (APC)-driven CRC mouse model (Apc(Min/+)) significantly improves su...
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| 發表在: | Oncogene |
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| Main Authors: | , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867492/ https://ncbi.nlm.nih.gov/pubmed/26300002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.305 |
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