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Intestinal-specific activatable Myb initiates colon tumorigenesis in mice
Transcription factor Myb is overexpressed in most colorectal cancers (CRC). Patients with CRC expressing the highest Myb are more likely to relapse. We previously showed that mono-allelic loss of Myb in an Adenomatous polyposis coli (APC)-driven CRC mouse model (Apc(Min/+)) significantly improves su...
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| Gepubliceerd in: | Oncogene |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867492/ https://ncbi.nlm.nih.gov/pubmed/26300002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.305 |
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