Intestinal-specific activatable Myb initiates colon tumorigenesis in mice

Transcription factor Myb is overexpressed in most colorectal cancers (CRC). Patients with CRC expressing the highest Myb are more likely to relapse. We previously showed that mono-allelic loss of Myb in an Adenomatous polyposis coli (APC)-driven CRC mouse model (Apc(Min/+)) significantly improves su...

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Bibliografische gegevens
Gepubliceerd in:Oncogene
Hoofdauteurs: Malaterre, J, Pereira, L, Putoczki, T, Millen, R, Paquet-Fifield, S, Germann, M, Liu, J, Cheasley, D, Sampurno, S, Stacker, S A, Achen, M G, Ward, R L, Waring, P, Mantamadiotis, T, Ernst, M, Ramsay, R G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867492/
https://ncbi.nlm.nih.gov/pubmed/26300002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.305
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