Intestinal-specific activatable Myb initiates colon tumorigenesis in mice

Transcription factor Myb is overexpressed in most colorectal cancers (CRC). Patients with CRC expressing the highest Myb are more likely to relapse. We previously showed that mono-allelic loss of Myb in an Adenomatous polyposis coli (APC)-driven CRC mouse model (Apc(Min/+)) significantly improves su...

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書目詳細資料
發表在:Oncogene
Main Authors: Malaterre, J, Pereira, L, Putoczki, T, Millen, R, Paquet-Fifield, S, Germann, M, Liu, J, Cheasley, D, Sampurno, S, Stacker, S A, Achen, M G, Ward, R L, Waring, P, Mantamadiotis, T, Ernst, M, Ramsay, R G
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867492/
https://ncbi.nlm.nih.gov/pubmed/26300002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.305
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