The Myb-p300-CREB axis modulates intestine homeostasis, radiosensitivity and tumorigenesis

The gastrointestinal (GI) epithelium is constantly renewing, depending upon the intestinal stem cells (ISC) regulated by a spectrum of transcription factors (TFs), including Myb. We noted previously in mice with a p300 mutation (plt6) within the Myb-interaction-domain phenocopied Myb hypomorphic mut...

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Detalhes bibliográficos
Main Authors: Sampurno, S, Bijenhof, A, Cheasley, D, Xu, H, Robine, S, Hilton, D, Alexander, W S, Pereira, L, Mantamadiotis, T, Malaterre, J, Ramsay, R G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641342/
https://ncbi.nlm.nih.gov/pubmed/23618903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.119
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