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Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity

The loss of skeletal muscle mass is observed in many pathophysiological conditions, including aging and obesity. The loss of muscle mass and function with aging is defined as sarcopenia and is characterized by a mismatch between skeletal muscle protein synthesis and breakdown. Characteristic metabol...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Rivas, Donato A., McDonald, Devin J., Rice, Nicholas P., Haran, Prashanth H., Dolnikowski, Gregory G., Fielding, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867383/
https://ncbi.nlm.nih.gov/pubmed/26764052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00198.2015
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