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Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity

The loss of skeletal muscle mass is observed in many pathophysiological conditions, including aging and obesity. The loss of muscle mass and function with aging is defined as sarcopenia and is characterized by a mismatch between skeletal muscle protein synthesis and breakdown. Characteristic metabol...

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Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Rivas, Donato A., McDonald, Devin J., Rice, Nicholas P., Haran, Prashanth H., Dolnikowski, Gregory G., Fielding, Roger A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867383/
https://ncbi.nlm.nih.gov/pubmed/26764052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00198.2015
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