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Silencing of CD24 enhances the PRIMA-1-induced restoration of mutant p53 in prostate cancer cells
PURPOSE: In prostate cancer (PCa) cells, there is CD24-dependent inactivation of mutant p53, but the mechanism and its significance remain largely unknown. Here, we validated this observation and explored the therapeutic potential of targeting CD24 in TP53 mutant PCa cells. EXPERIMENTAL DESIGN: Over...
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| Publicado no: | Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867243/ https://ncbi.nlm.nih.gov/pubmed/26712693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1927 |
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