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MicroRNA-1205, encoded on chromosome 8q24, targets EGLN3 to induce cell growth and contributes to risk of castration-resistant prostate cancer

The chromosome 8q24.21 locus, which contains the proto-oncogene c-MYC, long non-coding RNA PVT1, and microRNAs (miRs), is the most commonly amplified region in human prostate cancer. A long-range interaction of genetic variants with c-MYC or long non-coding PVT1 at this locus contributes to the gene...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, Yicun, Li, Xin, Liu, Wei, Li, Bingjin, Chen, Dongquan, Hu, Fengping, Wang, Lizhong, Liu, Xiaoguang M., Cui, Ranji, Liu, Runhua
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565506/
https://ncbi.nlm.nih.gov/pubmed/30808975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0760-3
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