[123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease.

OBJECTIVES: The main neuropathological feature in Parkinson's disease is a severe degeneration of the dopaminergic neurons in the substantia nigra resulting in a loss of dopamine (DA) transporters in the striatum. [123I]beta-CIT single photon emission computed tomography (SPECT) studies have de...

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Détails bibliographiques
Auteurs principaux: Booij, J, Tissingh, G, Boer, G J, Speelman, J D, Stoof, J C, Janssen, A G, Wolters, E C, van Royen, E A
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC486723/
https://ncbi.nlm.nih.gov/pubmed/9048712
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