[123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease.

OBJECTIVES: The main neuropathological feature in Parkinson's disease is a severe degeneration of the dopaminergic neurons in the substantia nigra resulting in a loss of dopamine (DA) transporters in the striatum. [123I]beta-CIT single photon emission computed tomography (SPECT) studies have de...

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Main Authors: Booij, J, Tissingh, G, Boer, G J, Speelman, J D, Stoof, J C, Janssen, A G, Wolters, E C, van Royen, E A
格式: Artigo
語言:Inglês
出版: 1997
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC486723/
https://ncbi.nlm.nih.gov/pubmed/9048712
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